Lethal Diltiazem Poisoning

Lethal Poisoning with p-Nitroaniline

A 15 year old boy died after ingestion of an unknown amount of p-nitroaniline with seizures and extremely wide pupils. A MetHb concentration of 36.8 % was photometrically determined in the blood sample collected during autopsy four days after death. By HPLC-DAD and GC-MS p-nitroaniline (4.2 μg/ml) and its metabolites 2hydroxy-4-nitroaniline (1.5 μg/ml), p-nitroacetanilide (0.38 μg/ml), p-phenyl...

Severe Diltiazem Poisoning Treated with Hyperinsulinaemia-Euglycaemia and Lipid Emulsion

Introduction. Calcium channel blockers (CCBs) drugs are widely used in the treatment of cardiovascular diseases. CCB poisoning is associated with significant cardiovascular toxicity and is potentially fatal. Currently, there is no specific antidote and the treatment of CCB poisoning is supportive; however, this supportive therapy is often insufficient. We present a clinical case of severe dilti...

Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning

Background: Acrylamide (C3H5NO) is a vinyl monomer. This water-soluble crystalline solid is a colorless, odorless agent which is used in scientific laboratories and some industries. Acrylamide has cellular oxidative effects. Acute or chronic poisoning with this agent happens as a result of skin, respiratory, or oral contacts. Clinical manifestations depend on the dose, duration, and frequency...

[Lethal sodium chlorate poisoning of two newborn].

A lethal danger in the home: turpentine poisoning.

Turpentine is an oleoresin obtained from various species of pine. In turpentine poisoning, various signs and symptoms of toxicity may develop, including hematuria, renal failure, loss of vision, chest pain, vomiting, severe coughing, gastroesophageal hemorrhage, hypotension, swelling of the throat and even death. We report a case of turpentine ingestion in a 9-year-old boy. The patient was admi...